The tumor microenvironment (TME) consists of a complex mix of cellular and non-cellular components, including immune cells, ...

See how small bits of non-coding RNA target mRNA for destruction and regulate gene expression. Evidence has also shown that siRNA is involved in antiviral defense in certain plant and animal species.

The startup’s first prospect is a heart medicine that works differently than the hypertrophic cardiomyopathy drugs developed ...

Diederichs pooled the RNA samples from each group and analyzed the differences in gene ... that inhibit expression of tumor and metastasis suppressor genes, among others. HOTAIR has so far been linked ...

Ribonucleic acid (RNA) is a form of nucleic ... involved in the differential regulation of gene expression. In 1993, microRNAs were recognized as small non-coding RNAs with a regulatory function ...

Researchers have now mapped lncRNA (long non-coding RNA molecules ... controlled by so-called regulatory RNA molecules, i.e. RNA molecules that regulate gene activity and include both lncRNAs ...

Three unrelated children with deletions of CHASERR, a long non-coding RNA, had a severe neurological ... t make proteins but are needed to regulate gene expression. CHASERR lies immediately ...

I am a biophysicist currently developing genomic tools to understand RNA biology. My long-term goals are to characterize how genetic information encoded in RNAs, both in coding and non-coding ...

TComparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases (Image: Wikimedia Commons, CC SA 3.0) The nucleotides are connected through phosphodiester bonds, ...

Noncoding RNAs are well known for their ability to control gene expression in cells. And as scientists have demonstrated repeatedly, protein production can be affected not just by RNAs made in the ...

It is the first big biopharma group to tap into Haya's platform, which identifies genes coding for long non-coding RNA ... which often involve control of gene expression and the regulation ...