Several genes linked to NASH development are associated with lipid droplets, including HSD17B13 which encodes a metabolic enzyme in the lipid droplet membrane. CN Bio’s liver-on-a-chip, cultured under ...

In a stride toward enhancing cancer treatment, University of Birmingham researchers are using organ-on-a-chip technology to imitate the liver's environment and improve immunotherapy for liver cancer.

Both half-life and intrinsic clearance are calculated based on the data from the assay of metabolic stability. We identify drug metabolites from liver microsomes (e.g., mouse, rat, dog, and human) and ...