Study: Structure of apolipoprotein B100 bound to the low-density lipoprotein receptor. Image Credit: Nemes Laszlo / Shutterstock. In a recent study published in the journal Nature, researchers ...

A team of biochemists has elucidated the 3-dimensional structure of a low-density lipoprotein (LDL) receptor during 1 stage of the process in which it releases LDL. Although there is no immediate ...

Fatty acids and steroids such as LDL cholesterol (a leading cause of heart disease and hardening of the arteries) are transported through the bloodstream by lipoproteins. Studying lipoprotein ...

Lipoprotein(a) is a presumed risk factor for atherosclerotic cardiovascular disease. Olpasiran is a small interfering RNA that reduces lipoprotein(a) synthesis in the liver. We conducted a ...

Elevated lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting hepa ...

Study: Lipoprotein(a) and the risk of recurrent coronary heart disease: the Dubbo Study. Image Credit: SUWIT NGAOKAEW / Shutterstock.com. Background. The lipoprotein(a) structure consists of a low ...

Excess cholesterol in low-density lipoproteins (LDL) is one of the strongest biomarkers for heart disease, but researchers have struggled to pin down the structure of apolipoprotein B100 (ApoB100 ...

Study elucidated how apoA-I mitigates the function of HDL. University of Cincinnati (UC) researchers have determined the structure of human HDL cholesterol. They say their understanding of how the ...

Reimund M, Dearborn AD, Graziano G, et al. Structure of Apolipoprotein B100 bound to low-density lipoprotein receptor. Nature , 2024 DOI: 10.1038/s41586-024-08223-0 Cite This Page : ...