DNA transformation and plasmid transformation are the same thing: the uptake of genetic material from the environment by “competent” cells. However, linear DNA is either incorporated into the host ...

If you ask a biologist if humans have circular DNA, they are likely to say 'no.' That is because eukaryotic cell nuclei have linear chromosomes, while prokaryotes have circular nucleoids and plasmids.

Aldevron’s Alchemy™ is an exclusive cell-free DNA technology which cuts research grade linear DNA manufacturing time by over 50 percent, accelerating mRNA development projects with cleaner ...

The manuscript, "A Linear DNA Vaccine Candidate Encoding the SARS-CoV-2 Receptor Binding Domain Elicits Protective Immunity in Domestic Cats," is available in preprint on bioRxiv and will be ...

Cornell University researchers have discovered a new mechanism these genes use to survive and propagate in bacteria with linear DNA, with applications in biotechnology and drug development.

To my surprise, this linear form of SV40 DNA was infectious. But when I recovered the SV40 DNA and looked at it, it was no longer linear. It had become super-coiled circular DNA again. And the EcoRI ...

To summarize, the intramuscular delivery of the novel linear DNA SARS-CoV-2 vaccine aided by electroporation was determined to be safe and elicited humoral and cellular immune responses.