University of Missouri researchers and collaborators have developed a new chemical tool that could help lower the cost of ...

In biology, the binding of cellular proteins to molecules called ligands produces myriad functions essential for life, including cell signaling and enzymatic action. In biotechnology and medicine, the ...

The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, targeted drug delivery and sustainable bioremediation.

"We rely solely on initial protein sequences and ligand SMILES strings." SMILES, or the Simplified Molecular Input Line Entry System, is a longstanding specification of the structure of molecules ...

A novel geometric deep learning framework designs ligand-specific protein binders, enhancing therapeutic potential in cell therapies and synthetic biology.

University of Missouri researchers and collaborators have developed a new chemical tool that could help lower the cost of ...

The small molecules used to control the RNA switch can be any cellular biomolecule, including metabolites, siRNA, miRNA, or proteins. In fact, it has been possible to engineer the ribozyme as a sensor ...

In this kind of cell, insulating organic molecules are used as ligands around ... requires lengthy purification and ligand exchange processing,” the Spanish group specified.