Colony-forming cell assays indicated that the leukemic bone marrow (BM) plasma inhibited erythroid colony formation, whereas they had no inhibitory effect on other types of colonies. Cytokine ...

The mechanisms of HSC maintenance are hijacked during the leukemogenic transformation of hematopoietic stem/progenitor cells into a rare population known as leukemic stem cells (LSC) or ...

The Kharas lab is working to identify critical pathways in both normal and leukemic hematopoietic cells. MSK investigators have used a lab tool originally developed to study fly nerve cells to uncover ...