Han is eager to continue exploring the relationships between these different brain circuits. “In the study, we showed that PACAP neurons in the lateral parabrachial nucleus extensively receive ...

More information: Prannay Reddy et al, Converging inputs compete at the lateral parabrachial nuclei to dictate the affective-motivational responses to cold pain, Pain (2024). DOI: 10.1097/j.pain ...

Another pathway from the spinal cord to the lateral parabrachial nucleus mediates the generation of discomfort to drive cold-seeking (or heat-avoidance) behaviors. This pathway also leads to the ...