For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life. A new study from King ...

The first is a genetically modified T cell with a chimeric antigen receptor that by itself does not recognize tumor antigens and is therefore not directly activated by them. The second component ...

Receptors on the surface of cytotoxic T cells recognize peptides presented by major histocompatibility complex (MHC) molecules on the tumor cell membrane. CD8 acts as a T-cell co-receptor that ...

C.M. Laumont et al., “Noncoding regions are the main source of targetable tumor-specific antigens,” Sci Transl Med, 10:eaau5516, 2019. In pursuit of safe and effective cancer therapies, researchers ...

In this case, the tumor on the right was irradiated; the left one was not ... Ruggiero A, Holland JP, Hudolin T, Shenker L, Koulova, A, Bander N, Lewis JS, Grimm J (2011) Targeting the internal ...