为探究运动改善认知的机制，研究人员对比皮质酮（CORT）和脑源性神经营养因子（BDNF）对海马长时程增强效应（LTP）的影响。发现 CORT 无单独作用，BDNF 增强 LTP，二者联用效果更显著且使 PKA 磷酸化，这或为运动改善认知提供新视角。 运动能改善学习和记忆 ...

Figure 1: Inhibiting postsynaptic expression of Syt1 and Syt7 blocks LTP by a cell-autonomous mechanism. Figure 2: Inhibiting postsynaptic Syt1 and Syt7 expression by various molecular ...

TrkB, a neurotrophin receptor tyrosine kinase well known for its functions during nervous system development, has recently emerged as a potent regulator of hippocampal long-term potentiation (LTP ...