Findings show potential for new lipid-based delivery formulations as a platform technology for immunizationPhiladelphia, PA, ...

撰文丨王聪编辑丨王多鱼排版丨水成文脂质纳米颗粒（LNP）在靶向肝，以及脾脏和肺部等主要器官方面已取得成功，但穿越血脑屏障（BBB）仍是一项重大挑战。有效的大脑靶向递送系统对于推进神经疾病基因治疗至关重要，但目前仍受限于低运输效率和核酸稳定性差的问题。

脂质纳米粒（LNP）制备溶液的奥秘：开启 mRNA 疗法优化新征程 在生命科学 ... 成为罕见病治疗领域的新曙光。而脂质纳米粒（Lipid nanoparticles，LNPs）作为 mRNA 疗法的 “黄金搭档”，凭借着独特的优势，成为了核酸递送的先进载体。它能够像 “护盾” 一样包裹 ...

Targeted CRISPR lipid nanoparticles eliminated 50% of tumors in mice with head and neck cancer.

Shares of Prime Medicine ( PRME -0.25%) are surging on Thursday. The gene-editing company's stock gained 10.5% as of 2 p.m.

News of a fresh investigational program was putting some zip into the shares of gene-editing company Prime Medicine (NASDAQ: ...

Prime Editing has potential to be best-in-class approach for AATD ---- Previously undisclosed program now emerging from within liver platform; ...

Generation Bio Co. (Nasdaq:GBIO), a biotechnology company working to change what’s possible for people living with T cell-driven autoimmune diseases, reported business highlights and fourth quarter ...

Daiichi Sankyo is stepping up its interest in RNA therapies, teaming with Nosis Biosciences to design drug candidates capable ...

Prime Medicine's program leverages the Company's universal liver lipid nanoparticle (LNP) to edit the E342K (Pi*Z) mutation in the SERPINA1 gene, the prevalent disease-causing mutation in AATD, ...