为探究孕激素（P4）维持孕期子宫静止的机制，研究发现 P4 激活 Kir7.1 通道，这对防治早产意义重大。 早产，这个看似简单的医学词汇，背后却隐藏着巨大的健康危机。它指的是妊娠不满 37 周就分娩的情况，是导致围产期母婴发病和死亡的重要原因。每年 ...

Figure 1: Depolarization of hypothalamic PVN MC4R neurons by α-MSH is G-protein independent. Figure 2: α-MSH depolarizes and AgRP hyperpolarizes hypothalamic PVN MC4R neurons by regulating Kir7 ...

High-Throughput Functional Evaluation of Melanocortin Compounds at the MC4R-Kir7.1 Complex: Biased Signaling at the Melanocortin 4 Receptor Never miss a story ...