Results and conclusion: The minimum requirement for selenium is that which prevents the deficiency disease, Keshan disease. The recommended intakes of selenium have been calculated from the ...

Taken together, these data suggest that there is a variety of potential mechanisms involving antioxidant selenoproteins (Figure 3) that conspire to produce the cardiomyopathy of Keshan disease.

Keshan disease is a form of cardiomyopathy, which is the term for conditions that affect the heart muscle. It may develop as a result of a selenium deficiency. A person can usually manage the ...