Next time you feel an itch, remember that your brain's vast network of neurons informs it whether it is an itch or pain. A ...

Are these neurons part of the long sought-after neural pathway for itch? The answer to this question could be important for the development of antipruritogenic drugs. Chronic itch is a ...

These findings challenge the conventional assumption that pain and itch signals follow overlapping pathways and instead highlight distinct neural mechanisms for each sensation. Given that the ACC ...

Nppb-knockout mice did not respond to itch-inducing compounds, suggesting that the protein is required to produce the itch sensation. The team found Nppb receptors on spinal cord neurons that release ...

In a nutshell While scratching worsens allergic skin conditions like eczema by increasing inflammation, it also activates a ...

A new study reveals that pain and itch are processed by distinct neural circuits in the anterior cingulate cortex (ACC).

3. Itches have their own nerve network Until recently we thought that itch and pain both shared the same pathways, but in 1997 a ground-breaking discovery revealed that the itch has its own ...

Their findings, published in Nature Communications, reveal that separate neuronal populations in the anterior cingulate cortex (ACC) selectively process pain and itch, challenging previous assumptions ...