Such collaborations may take different forms: delivering novel monoclonal antibodies or other biologics to their intracellular target; improving the biodistribution of novel small molecules with ...

It wouldn’t be surprising to discover new types of membrane manipulation, Mukherjee says, adding that the behavior offers a versatile way to exert influence over everything from cell division to the ...

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal ...

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

However, CAR T-cell therapy thus far has been largely restricted to targeting extracellular tumor ... that is reactive to a peptide portion of the intracellular onco-protein Wilms Tumor 1(WT1 ...

Akribion Therapeutics emerges from stealth with €8 million in seed funding to develop a novel cancer RNA-guided approach ...

These translocation products are problematic as therapeutic targets because of their intracellular location. We discuss emerging molecular-based technologies for targeting chromosomal ...

Mizuho Securities analyst Graig Suvannavejh reiterated a Buy rating on Intra-Cellular Therapies (ITCI – Research Report) today and set a price ...