Here we utilize multiple mouse genetic models to uncover a role for PI3KC2α in regulating the internal membrane reserve structure of megakaryocytes (demarcation membrane system) and platelets ...

There’s the membrane-bound nucleus, safekeeper of the genome. There’s a whole system of internal membranes: the endoplasmic reticulum, the Golgi apparatus, lysosomes, peroxisomes and vacuoles ...

Despite its apparent important function, until now it was not clear how this specialized internal membrane system is actually formed. In a collaborative project, researchers have now identified ...

Despite its apparent important function, until now it was not clear how this specialized internal membrane system is actually formed. In a collaborative project, researchers at Johannes Gutenberg ...

There’s the membrane-bound nucleus, safekeeper of the genome. There’s a whole system of internal membranes: the endoplasmic reticulum, the Golgi apparatus, lysosomes, peroxisomes and vacuoles ...

Despite its apparent important function, until now it was not clear how this specialized internal membrane system is actually formed. In a collaborative project, researchers at Johannes Gutenberg ...

Its finding: certain structural motifs of proteins in the ER membrane play a central role ... the expansion and networking of their internal canal system as needed. A process known as ER-phagy ...

The discovery that internal viscosity plays a crucial role in membrane behavior adds to the understanding of how cells function, with potential implications for biomedical applications such as drug ...

"These fiber systems imitate the extracellular ... They cause no foreign body reactions and no internal scarring. The innovative silica gel membrane releases only one degradation product, ortho ...

Using the internal perfusion system, ion channels regulated by internal binding sites for second messengers can be easily modulated or compounds acting on the internal side of the membrane like e.g.