Department of Medicine, University of Toronto, Women's College Hospital, and co-authors have found biologics targeting ...

Humanwell Healthcare (Group) Co. Ltd. has described proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to an interleukin-1 ...

Mevalonate kinase deficiency (MKD ... These medications block proteins that cause inflammation, like interleukin-1 (IL-1) and tumor necrosis factor (TNF), to prevent or cut down the number ...

ATI-2138 exhibits the ability to selectively and potently block interleukin-2-inducible T cell kinase (ITK) and Janus kinase 3 (JAK3), playing a key role in modulating T cell activity involved in ...