The FDA approved Dupixent for the treatment of adults with bullous pemphigoid, a rare skin disease often uncontrolled with ...

The FDA approved dupilumab (Dupixent) as the first targeted drug for bullous pemphigoid, a rare blistering skin disease that ...

The Food and Drug Administration (FDA) has approved Dupixent ® (dupilumab) for the treatment of adult patients with bullous pemphigoid.

Here we demonstrate that AIDS-KS cells express surface interleukin-4 (IL-4) receptors, and that IL-4 toxin (IL-4(38-37)-PE38KDEL) is specifically cytotoxic to these cells. Intratumoral ...

Image Credit: ACROBiosystems The biological and immunological functions of B-lymphocytes, monocytes, dendritic cells, and fibroblasts are all affected by the cytokines IL-4 and IL-13. These ...

This pathway is inhibited by interferon-γ and interleukin-4. The transcription factor (T-bet, ROR-γt, or GATA3) characteristic of each pathway is shown. R denotes receptor. Interleukin-23 can ...

In addition, various cytokines and growth factors produced by these cells, such as interleukin (IL)-4 (Leonard et al, 1997; Shi et al, 1998a), IL-5 (Shi et al, 1998b; Till et al, 1998), IL-10 ...

To the Editor: In 1997, Hershey et al. reported finding a mutation in the interleukin-4 receptor α allele in 13 of 20 patients with atopy, as compared with 5 of 30 control subjects. 1 This ...