Morphic Therapeutic has lost Johnson & Johnson's Janssen Pharma as a partner, following the termination of an alliance to develop drugs targeting integrins first agreed in 2019. In a filing with ...

Figure 1: α v β 3 as a mediator of antiangiogenic regulators. Figure 2: Trans-dominant inhibition of proangiogenic integrins. In presenting these models for negative regulation by α v integrins ...

Pliant Therapeutics, Inc.’s PLRX share price has dipped by 34.81%, which has investors questioning if this is right time to ...

The Fagerholm group studies the role of leukocyte integrins in various immune reactions. We are interested in the in vivo roles and regulation of leukocyte beta2-integrins in a healthy and ...

She hopes to understand how a protein’s structure influences its function. She uses cryo-EM to study integrins, proteins that help cells communicate and move. Integrins are more flexible than many ...

Firm leukocyte adhesion depends on leukocyte integrins, a family of transmembrane receptors, specialized for anchoring cells to the surrounding matrix or to other cells. After firm adhesion ...