To the Editor: Reliable and fast computation of protein free energy is crucial for protein-structure analysis ... protein interfaces (for example, the insulin dimer interface; Supplementary ...

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different ... in the blood to target cells Insulin: released from pancreas, stimulates ...

Figure 1: The signalling pathway by which insulin inhibits GSK3 and contributes to the stimulation of glycogen and protein synthesis. Figure 4: The molecular mechanism by which phosphorylation ...