Guidelines are urgently needed on the judicious use of cholinergic drugs. Cholinesterase inhibitors remain pivotal to the treatment of Alzheimer disease (AD), but no specific guidelines are ...

Several clinical trials, some of which remain unpublished, have attempted to determine whether treatment with cholinesterase inhibitors (ChEIs) can slow or prevent the conversion of MCI to ...

A study identifies senolytic compounds that can inhibit specific brain enzymes associated with Alzheimer’s disease (AD) while ...

This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by cholinesterase. Discontinue at the first sign of skin rash, unless not drug ...

It sees advancements with new drug classes like cholinesterase inhibitors. The global Alzheimer's disease therapeutics market size is projected to expand by $5.41b from 2024-2028 with an estimated ...

Applications are invited for a Postdoctoral Research Associate in biological chemistry with a particular emphasis on small molecule synthesis, enzyme kinetics and enzyme-small molecule binding studies ...

May antagonize ACE inhibitors, β-blockers, diuretics, cholinesterase inhibitors, uricosurics. May increase risk of renal dysfunction with NSAIDs. Monitor phenytoin, valproic acid, other ...