Immunoglobulin A (IgA) nephropathy is a condition that causes a certain type of protein to build up in your kidneys. It progresses differently in everyone. Your kidneys might still work well years ...

Immunoglobulin A nephropathy (also known as IgA nephropathy or Berger's disease) is a condition that causes IgA antibodies to accumulate in the kidneys—leading to damage that affects their blood ...

But, since IgA nephropathy may run in families, genetic and environmental factors probably contribute to developing the disease. Kidney disease usually cannot be cured. Once the tiny filtering ...

Atrasentan is approved for proteinuria reduction in primary IgA nephropathy, a condition risking kidney failure. The phase 3 ALIGN study showed atrasentan reduced proteinuria by 36.1% compared to ...