15 sIL-2R can present IL-2 to CD4+ T lymphocytes, leading to their differentiation into regulatory T cells (Tregs) instead of T-helper (Th)1 or Th17 lymphocytes, which can subsequently suppress ...

Details are as follows and available on the SITC website: Title: T cell and Immune Activation from a Phase 1 Study of STK -012, a First-in-class IL-2R α/ß Selective Partial Agonist in Advanced ...