IL-12 binding to interneurons causes them to ... and nerve fiber density changed depending on whether the IL-12 signaling pathway was present or absent. Mass spectrometric analyses (lipidomics ...

Interleukin 35 (IL-35) belongs to the IL-12 family of heterodimeric cytokines but has a distinct functional profile. IL-35 suppresses T cell proliferation and converts naive T cells into IL-35 ...

One such messenger is interleukin-12 (IL-12). Through meticulous analyses ... nerve fiber density changed depending on whether the IL-12 signaling pathway was present or absent.

IL-4 and IL-13 are closely related cytokines that are produced by Th2 cells. However, IL-4 and IL-13 have different effects on the development of asthma phenotypes. Here, we evaluated downstream ...

IL-12 binding to interneurons causes them to ... and nerve fiber density changed depending on whether the IL-12 signaling pathway was present or absent. Mass spectrometric analyses (lipidomics ...

Electron micrographs of mouse brain tissue taken at the Max Planck Institute for Multidisciplinary Sciences in Göttingen also showed how myelin structure and nerve fiber density changed depending on ...

It also activates the STAT4 pathway in T cells ... including CD4+ TCR-mediated promotion of IL-12 signaling to induce IFN-γ and peptide-mediated NK cell activation. This leads to tumor lysis ...

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to ...

IL-12 binding to interneurons causes them to ... and nerve fiber density changed depending on whether the IL-12 signaling pathway was present or absent. Mass spectrometric analyses (lipidomics ...