本综述深入探讨了缺氧（Hypoxia）、肿瘤干细胞特性（Cancer Cell Stemness）与药物耐受性（Drug Resistance）之间的复杂关系，揭示了其在肿瘤治疗中的关键作用。 肿瘤微环境中的缺氧是实体瘤的常见特征，与肿瘤的侵袭性、复发和治疗耐受性密切相关。缺氧能够诱导 ...

I n the complex landscape of cancer, tumors create their own microenvironment, often marked by low oxygen levels, a condition known as hypoxia. Hypoxia arises as tumors grow rapidly, outpacing ...

Antibiotics increase the gut oxygen levels and favor growth of harmful fungi. Chemically restoring intestinal gut hypoxia ...

I n the complex landscape of cancer, tumors create their own microenvironment, often marked by low oxygen levels, a condition ...

The team's findings were published in the paper "Functional reprogramming of neutrophils within the brain tumor microenvironment by hypoxia-driven histone lactylation," from Cancer Discovery.

“This trial marks an exciting step forward in addressing one of the key challenges in cancer immunotherapy. Hypoxia limits T-cell infiltration and suppresses immune responses, especially in ...