In mice, chronic exposure to inhaled hypoxia can normalize tissue hyperoxia and has been shown to extend lifespan in a mouse model of Leigh syndrome. Phase I clinical trials have demonstrated the ...

Background Mechanical stress on the heart is commonly considered the sole stimulus explaining the synthesis and release of circulating natriuretic peptides and their derivatives. While one of the most ...

This model differs from IHT since the intensity of the training stimulus is maximal and therefore allows one to maintain high FT recruitment so that positive results can be expected when adding ...

Finally, in their model of hypoxia, they showed that interfering with early inflammation prevents pulmonary hypertension from developing. In work recently published in Arteriosclerosis ...