Trials evaluating the use of hypertonic saline solutions for resuscitation after traumatic injury have not shown an overall mortality benefit compared with isotonic fluid administration.

Oral rehydration (reintroducing water into the body through the mouth) is the first-line treatment for hypertonic dehydration. This involves drinking an oral solution that contains adequate levels ...

Hypertonic saline refers to any saline solution with a concentration of sodium chloride (NaCl) higher than physiologic (0.9%). Commonly used preparations include 2%, 3%, 5%, 7%, and 23% NaCl.