Discover how biotechs and big pharma are developing novel treatments for high cholesterol with a range of different targets.

2022年6月18日，中国科学院上海药物研究所南发俊课题组和李静雅课题组合作在Acta Pharmaceutica Sinica B上发表文章“Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia”，在高胆固醇血症靶向治疗策略中取得重要进展 ...

Current guidelines strongly recommend the identification of genetic forms of hypercholesterolemia (HC) during childhood. The usefulness of non–cholesterol sterols (NCS) in the diagnosis of ...

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this journey through a disease state ...

The 37 familial hypercholesterolemia mutations are listed in Table S2 in the Supplementary Appendix; the list of mutations is ranked by the child’s associated cholesterol levels and also shows ...

What Is Homozygous Familial Hypercholesterolemia? Homozygous familial hypercholesterolemia is a disorder where it is hard for your body to remove LDL "bad" cholesterol from your blood.

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients ...

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this journey through a disease state ...

Side-effect and safety profiles were similar in the two groups. In patients with familial hypercholesterolemia, combined therapy with ezetimibe and simvastatin did not result in a significant ...

Still, it took nearly a year after her heart attack to be diagnosed with familial hypercholesterolemia (FH), an inherited genetic condition that causes people to be born with high levels of LDL ...

Anthropometric measurements, blood pressure values, and blood samples for lipid profile testing were obtained. Results: Hypercholesterolemia was present in 62.4% of Polish seniors (56.1% of men; 66.3% ...