Hydrolases are enzymes that catalyze the cleavage of a covalent bond using water. Types of hydrolase include esterases, such as phosphatases, that act on ester bonds, and proteases or peptidases ...

are an example of this conservation in action, and a boon to drug discovery. Abide Therapeutics is mining one such enzyme superfamily, the serine hydrolases (SHs). Comprising over 200 members ...