One of the key challenges of the modern genomics era is studying the thousands of genes in a single human cell at scale. To ...

为解决诱导调节性 T（iT reg ）细胞不稳定、阻碍转化应用的问题，研究人员开展全基因组 CRISPR 功能缺失筛选研究。结果发现 RBPJ–NCOR 复合物负调控 FOXP 3 ，敲除 RBPJ 可增强 iT reg 功能，该成果为改善自身免疫病细胞疗法提供新方向。

Recently several teams have deployed CRISPR in an attempt to eliminate HIV from the DNA of human cells. The results have been only partially successful, but many scientists remain convinced that ...

2月18日，《Cell》的研究“Reprogrammable RNA-targeting CRISPR systems evolved from RNA toxin-antitoxins”揭开了惊人真相——被称作"基因魔剪"的Cas13蛋白，竟起源于 ...

Scientists have found a way to study early embryonic development without real embryos. Using CRISPR, they programmed stem cells to self-organize into structures mimicking early embryos. The cells show ...

The CRISPR-Cas9 platform will be used to delete the PD-1 gene in T cells extracted from trial participant’s blood. In healthy cells, an activated PD-1 gene results in the production of the PD-1 ...

This study provides a potentially useful investigation into the positive role of BDNF/TrkB signaling in implanted dental pulp stem cells to enhance dentin regeneration in the context of dental caries.

Using CRISPR-based engineering methods to prompt stem cells to organize into embryo-like structures, scientists were able to create 'programmable' cellular models of embryos without ever experimenting ...

19, 2024 — Cell-to-cell communication through ... But only two percent of the human genome actually encodes ... Nov. 6, 2024 — The CRISPR tool is capable of repairing the genetic defect ...

License agreement provides Jumpcode Genomics access to CRISPR gene editing technology to enhance next-generation sequencing ...