Most siRNA oligonucleotides (oligos) for in vivo use are chemically synthesized duplexes of 21 to 23 oligos based on the original work of Tuschl ... large in size and do not readily diffuse ...

How does siRNA work, and what makes it so different? To target a particular gene via siRNA, researchers actually target its messenger RNA, an intermediary in protein production made by transcribing ...

The cash infusion will help fund preclinical work regarding a NanoJacket particle developed by the pair. It's designed to deliver siRNA to a cancer cell and cause cancer cell death by stopping a ...