Upper limb deformity may be bilateral but asymmetric or even unilateral. The most common forms of CHD associated with HOS are ASD, usually of the ostium secundum variety, and VSD, usually ...

Holt–Oram syndrome has been associated with mutations in the T-box transcription factor TBX5, but little is known about the function of this protein or how mutations in it cause disease.

Linda and Timmy Bannon both have Holt-Oram syndrome. — -- A Chicago mother and son who were both born without arms are an inspiring testament to overcoming obstacles. Linda Bannon ...

The first eight months of his life have been a battle, as doctors diagnosed him with Holt-Oram syndrome. The one in a 100,000 condition often leads to cardiac problems. But now smiling Noa is the ...

Imagine if you were born without any arms. How would you put on your make-up, text your friends, or eat with a knife and fork? Well, it hasn’t stopped 36-year-old Linda Bannon doing all of that.

Noa Gwilym Pritchard was born on February 10 this year with Holt-Oram syndrome, a genetic diseases that affects just one person in 100,000. People with the syndrome have abnormally developed bones ...