Positive-feedback loops and cooperativity among chromatin-modifying complexes are crucial for the propagation of histone marks. The nuclear architecture and long-range interactions are likely to ...

How the epigenetic machinery regulates these monoamine-derived histone modifications remained unclear. In the current work, Zheng et al. established the role of an epigenetic mark derived from ...

Aging involves complex cellular and molecular changes, including epigenetic modifications like Deoxyribonucleic acid (DNA) methylation and histone marks. Age predictors, or "clocks," have been ...

Results prove that inversions can be generated in plants without causing further unwanted changes in the expression of genetic information.

Image Credit: Love Employee/Shutterstock.com In a recent study published in Nature Metabolism, a group of researchers studied the impact of short-chain fatty acid (SCFA)-derived histone marks ...

While each cell contains the complete genetic blueprint of an organism, chemical marks on the DNA – so ... DNA sections by epigenetically modifying histone proteins that package the DNA.