The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

Histone H3 phosphorylation may initiate at different phases of the cell division in different organisms, but metaphase chromosomes are always found to be heavily phosphorylated. Upon exit of ...

Figure 2: Immunofluorescence patterns of human metaphase chromosomes stained with the Lys9-methyl H3 antibody ... Rice, J.C. & Allis, C.D. Histone methylation versus histone acetylation: new ...

Phosphorylation of core histones is crucial for chromosome condensation ... a platform for effector proteins. Histone phosphorylation at H2A on T120 and H3 at S10 are required for the compaction ...

Centromeres, specialized regions located at the center of chromosomes ... which contain eight histone proteins—two each of H2A, H2B, H3, and H4. However, centromeres feature a specialized ...

The cell skeleton, which distributes the chromosomes to the two daughter ... epigenetic centromere marking is a variant form of the H3 histone known as CenH3. Histone proteins bind the DNA largely ...

The CENP-A nucleosome is copied several times to create a unique epigenetic area, different from the rest of the chromosome. CENP-A replaces histone H3 in the nucleosomes located at the centromere.

Histones are the building blocks of chromatin, the structural support of chromosomes within a cell's nucleus. While histone H3 is particularly abundant in multicellular organisms such as plants ...

Researchers from Children's Hospital of Philadelphia (CHOP) have demonstrated that newly mutated variants of a key protein involved in supporting chromosomes ... of the H3.3 histone had any ...

Researchers identify a novel centromere-specific histone H3 variant called the “CENP ... Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper ...