Here, Wolfgang Junger discusses the importance of purinergic receptor signalling for fine-tuning immune cell responses. Autocrine signalling through purinergic receptors can both amplify and ...

Histamine is an amine that is produced as part of a local immune response to cause inflammation. It also performs several important functions in the bowel and acts as a neurotransmitter or ...

A new signaling pathway, which is important for the regulation of the immune response and inflammation, was discovered by an international team of scientists led by prof Ivan Dikic from the Goethe ...

Histamine is an autacoid, which means it acts similarly to a local hormone, near its site of synthesis. It is produced as part of the local immune response to invading bodies and triggers ...

Cancer cell-derived or allergic reaction-released histamine dampened antitumor immunity and conferred resistance to cancer immunotherapy, according to a retrospective study published in Cancer ...

A new signaling pathway, which is important for the regulation of the immune response and inflammation, was discovered by an international team of scientists led by prof Ivan Dikic from the Goethe ...

Research Suggests Interrupting Immune Response Improves Multiple Sclerosis Outcomes Mar. 22, 2022 — Multiple sclerosis is a chronic disease that damages neurons.

New synthetic receptor expands cellular control options, including immune response and neurological signaling. Story by ...

Inflammation – a blanket term describing an immune response – triggers the release of histamine in the body. This increases blood flow to affected areas to flood them with immune cells.

Our research uncovers a novel mechanism whereby CPI-613 enhances the immune response through the inhibition of THBS2 signaling associated with ER stress. These findings offer insights into the ...