为解决类风湿关节炎(RA)中滑膜成纤维细胞(FLSs)异常活化导致的关节破坏问题，河南大学人民医院团队揭示了circ_0002970通过调控 ...

The Hippo pathway, which controls tissue growth, and proteins that regulate apicobasal polarity have separately been implicated in renal cystogenesis. New research by Thomas Weide, Hermann ...

环状RNA(CircRNAs)和N6-甲基腺苷(M6A)修饰广泛参与多种肿瘤的进展，包括肝细胞癌(HCC)。然而，在HCC的发病机制中，CircRNA和m6A之间的串扰仍然难以捉摸 ...

Now, researchers at Osaka University have identified the disturbed molecular pathways and revealed the underlying mechanisms that may inform an effective and much-needed therapeutic strategy.

Among these signals, the TGF-β and HIPPO pathways are critical, functioning as tumor suppressors and regulating liver development and regeneration. The review focuses on these pathways' interplay ...

The research examined the Hippo signaling pathway, an evolutionarily conserved signaling pathway that plays a complex role in cellular function as a major pathway promoting fibrosis in systemic ...