Hepcidin, which is encoded by the Hamp gene, regulates the absorption of iron from the intestines, recycling by macrophages, and release of stored iron from hepatocytes. The protein HFE regulates ...

Rusfertide, according to the National Cancer Institute, mimics endogenous hepcidin, a protein primarily produced in hepatocytes in the liver and increases hepcidin levels. The drug may work to ...