Described in an article published in Science, their tool, called Helicase-Assisted Continuous Editing (HACE), can be deployed to predetermined regions of the genome in intact, living cells.

Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA strands, thereby pulling apart the two strands. As the helicase moves along the DNA ...

The RF is a multiprotein complex with helicase and DNA synthesis activities. It is called a fork because the structure resembles a two-pronged fork. The helicase activities unwind DNA in front of ...

A search for Npw38-interacting molecules revealed that Npw38 can interact with NpwBP, DNA helicase, RNA helicase, RNA, and single-stranded DNA to form a nuclear protein complex which may be involved ...