然而,目前对于不同方法实现 HSCs 体内转导的系统研究较少。本研究旨在开发并优化 AAV 载体实现 HSCs 体内转导的方法,系统比较不同转导途径,重点研究 AAV6 在体内 HSC 基因治疗中的应用。 本研究表明 AAV6 载体可高效在体内转导功能性 HSCs,并提供了优化的体内 ...
为探究肝星状细胞(HSCs)非纤维化功能,研究人员发现 HSCs 通过 R-spondin 3(RSPO3)调控肝脏,为肝脏疾病治疗提供新方向。
在分子水平上,研究人员发现,Lhx2能通过上调肝星状细胞中HGF的表达来促进肝细胞的增殖,其还能通过上调阻断TGF-β信号通路的SMAD6分子来抑制肝星状细胞的激活和纤维化发生。本文研究在分子、细胞和动物水平上系统性地阐明了肝星状细胞在肝脏再生和纤维 ...
New research suggests that frequent blood donation can trigger genetic changes that might protect certain stem cells from ...
HEART TEST LABORATORIES ($HSCS) posted quarterly earnings results on Thursday, March 13th. The company reported earnings of -$2.57 per share, missing estimates of -$2 ...
3 天on MSN
An international group of researchers has identified an important mechanism that enables stem cells to evade immune rejection ...
15 天
News-Medical.Net on MSNUCSF study reveals lungs as source of hematopoietic stem cellsRed blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion ...
HeartSciences (HSCS) announced that it has engaged Integrous Communications, a premier investor relations firm, to enhance communication ...
A new UCSF study shows that the human lungs have just as many blood-producing stem cells as bone marrow. These stem cells are ...
present an important study that applied a high-resolution transposon-based barcoding system to show the clonal contribution of hematopoietic stem and ...
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