In this article we give an overview of RNA-based HPV diagnostics and the role of E6/E7 mRNA detection as a predictive marker for the development of cervical carcinoma. HPV E6/E7 mRNA testing for ...

Some human papillomavirus (HPV) tests check for mRNA E6/E7. E6 and E7 are proteins present in types of HPV viruses that carry a high risk of cancer. A positive test result indicates that a person ...

Accurate screening of HPV-driven head and neck squamous cell carcinoma is a critical issue. HPV status is currently used as a prognostic marker and to interpret the outcomes of clinical trials ...

the Venice cervical screening program introduced a HPV mRNA-based protocol. The Aptima HPV Assay, a test to detect HR-HPV E6/E7 mRNA (Hologic), replaced cytology as the primary test for the entire ...

In a clinical study designed to detect human papillomavirus (HPV) E6/E7 mRNA in routine clinical specimens of head and neck cancer, HPV status determined by the RNAscope HPV test was highly predictive ...

Advanced Cell Diagnostics, Inc. (ACD) today announced the results of its clinical study utilizing RNAscope™ technology to detect human papillomavirus (HPV) E6/E7 mRNA in routine clinical ...

2011. Aptima HPV E6/E7 mRNA Test Is as Sensitive as Hybrid Capture 2 Assay but More Specific at Detecting Cervical Precancer and Cancer. J. Clin. Microbiol. 49: 557-564.) ...

IncellDx’s HPV OncoTect ® E6/E7 mRNA Kit Greatly Increases Specificity Compared to Other HPV tests and was Successfully Used in a Large Clinical Trial in Women Under 30 Years of Age.

Nutcracker’s presentation on NTX-250 will describe how its three RNA-encoded protein components (HPV E6/E7, IL-12 ... on NTX-471 will describe unique mRNA compositions that can selectively ...

Gen-Probe is currently developing the APTIMA HPV Assay, targeting E6/E7 mRNA from 14 carcinogenic HPV genotypes. A prototype of this assay was evaluated recently in 536 women with histological ...