Since the complete sequencing of a human major histocompatibility complex (MHC) haplotype, interest in non-human leucocyte antigen (HLA) genes encoded in the MHC has been growing. Non-HLA genes ...

The HLA complex on chromosome 6 contains over 200 genes, more than 40 of which encode leukocyte antigens (). 1–3 The rest are an assortment of genes that are not evolutionarily related to the ...

Major-histocompatibility-complex alleles determine the tissue compatibility that is necessary for the acceptance of transplanted tissues. 1 Graft survival after kidney and heart transplantation is ...

Adoptive transfer of genetically modified T cells is being explored as a treatment for patients with metastatic cancer. Most current strategies use genes that encode major histocompatibility complex ...

The Major Histocompatibility Complex Class I Chain-Related Gene A (MICA) Reference Panel is derived from 39 samples studied at the 13th workshop in the disease division studying innate immune ...

The major histocompatibility complex (MHC), or Human Leukocyte Antigen (HLA) complex, is essential for immunorecognition, organ and stem cell transplantation, and disease association, including ...

Myrio's PHOX2B PC-CAR T therapy gains FDA approval for human trials, promising innovative treatment for patients with ...

Haplotyping in 3-D – Long-distance phasing of short NGS reads – a novel approach to HLA haplotyping. Lind C, Morris T, Willis A, et al.

For HLA laboratories, CareDx offers NGS-based typing solutions with AlloSeq Tx, 1 QTYPE, 1 SSP, and mTilda LIMS (Laboratory Information Management System).

The Histocompatibility and Immunogenetics (H&I) Laboratory provides a complete range of diagnostic testing services used primarily in the field of clinical organ transplantation and, secondarily, for ...