HIV（人类免疫缺陷病毒）感染是全球重大健康难题。这篇研究聚焦 HIV-1 感染的巨噬细胞与 CD4 + T 细胞的相互作用，发现非感染性 CD4 + T 细胞可促进原代 HIV-1 在巨噬细胞中复制并形成 VCCs（病毒储存区室），为攻克 HIV 感染提供新方向，值得关注。 研究背景 自 1983 ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Most HIV-negative adults have between 500 and 1500 CD4 cells in a cubic millimeter of blood ... They help the other immune cells to launch a well-coordinated attack when there is an intruder such as a ...

Two research teams led by Warner Greene at the Gladstone Institutes in San Francisco have demonstrated that the vast majority of CD4 T cells in lymphoid tissues, despite their ability to resist full ...

Medically reviewed by Anju Goel, MD HIV and AIDS are related, but they are not the same thing. HIV (human immunodeficiency ...

Pneumococcal infections are common in people living with HIV, even with higher CD4 cell counts. Vaccination and HIV treatment reduce the risk of invasive pneumococcal disease. Pneumococcal disease is ...

Specifically, HIV attacks CD4 cells, which are also called T cells. CD4 cells are a type of white blood cell. They help direct how your immune system responds to an infection. Without treatment ...

HIV (human immunodeficiency virus) is a viral infection transmitted through the sexual route. Intravenous needle sharing, infected blood transfusions and transmission from mother to child during ...