Introduction: Mutations of hepatitis B virus (HBV) polymerase, especially occurring at the highly conserved YMDD region, are related to resistance to lamivudine. Although these mutations are ...
We found that patients who had YMDD mutations did not always have breakthrough of HBV DNA or ALT simultaneously (Fig. 2). Conversely, breakthrough of HBV DNA and/or ALT was not always the result ...
As part of their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) can establish an infection in liver cells, researchers led by teams at Memorial Sloan ...