Conversion of HA0 to HA is depending on the pathogenicity of influenza A viruses: extracellular conversion for low pathogenic influenza A viruses and intracellular conversion for highly pathogenic ...

Conversion of HA0 to HA is depending on the pathogenicity of influenza A viruses: extracellular conversion for low pathogenic influenza A viruses and intracellular conversion for highly pathogenic ...

HA is initially synthesized by host cells in its precursor form that known as HA0. Conversion of HA0 to HA is depending on the pathogenicity of influenza A viruses: extracellular conversion for low ...

Conversion of HA0 to HA is depending on the pathogenicity of influenza A viruses: extracellular conversion for low pathogenic influenza A viruses and intracellular conversion for highly pathogenic ...

In this study, we combined the mucosal adjuvant alpha-galactosylceramide ({alpha}GalCer) and peptides designed across the highly conserved influenza precursor haemagglutinin (HA0) cleavage loop as a ...

Furin regulates viral tropism. The fusion protein precursor HA0 of avian influenza viruses is cleaved by furin. Avian influenza viruses that lack the furin site in HA0 infect the intestinal tract.