Three of these six pathogens are antibiotic-resistant Gram-negative bacteria. Recently, antibacterial drugs against ESBL-producing Gram-negative bacteria accounted for ∼15% (2 out of 13 ...

TN 1893 Pfeiffer observed that the intraperitoneal injection of the cholera vibrio into mice resulted in the lysis of the injected bacteria by the host defense mechanisms. After this lysis the ...

Notably, no resistance determinants ... mechanism of action could pave the way for developing next-generation antibiotics ...