Infections by multidrug resistant organisms (MDROs) are a global health threat with a worrying increasing trend. In fragile ...

First, gram-negative bacteria have a thin cell wall that is about 1.5 to 10 nanometers across, whereas gram-positive bacteria have a thick cell wall measuring about 20 to 80 nanometers.

Three of these six pathogens are antibiotic-resistant Gram-negative bacteria. Recently, antibacterial drugs against ESBL-producing Gram-negative bacteria accounted for ∼15% (2 out of 13 ...

Purpose. The appropriateness of combination therapy for infections caused by gram-negative organisms is examined. Summary. Mortality from Pseudomonas aeruginosa infection is particularly high ...

Gram-positive cell walls have a thick peptidoglycan layer beyond the plasma membrane. Characteristic polymers called teichoic and lipoteichoic acids stick out above the peptidoglycan and it is because ...

A team of researchers at the University of California, Los Angeles (UCLA) has introduced a virtual Gram staining technique that could transform how microbiologists stain and classify bacteria.

“We identified and developed two small molecules that inhibit a protein in the lipopolysaccharide synthesis pathway in the cell wall of the gram-negative bacteria,” Anders Karlén, one of the ...