Uric acid crystals can accumulate under the skin and form lumps called "tophi." Chronic (long-term) gout can cause knee joints to become deformed, leading to constant pain and limited mobility or ...

Her general practitioner diagnosed gouty arthritis because of a high serum uric-acid level (600 µmol/l; normal range 270–380 µmol/l) coexistent with tophi in her hands, and initiated ...

MDedge News, December 15, 2022 ACR 2022 Intensive Gout Treatment Meets Urate Goal, Lowers Tophi Burden The second randomized trial of therapy to intensively lower urate for patients with gout ...

According to experts, tophi can form in any of the following body parts: Swelling in joints due to high uric acid is caused by gout – as excess uric acid in the blood forms crystals that deposit ...

and dissolve tophi in gout and tophaceous gout patients, today announced the completion of enrollment for its pivotal global Phase 3 REDUCE 2 trial. "We would like to thank the gout community for ...