The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

Tophaceous gout is a severe form of gout. It results when uric acid crystals form, leading to growths called tophi around the ...

Gout patients frequently have a number of comorbidities, including obesity, hypertension, high serum lipid and cholesterol levels, kidney disease, diabetes, and cardiovascular disease. [2,7,19 ...

an increased frequency of gouty attacks and with the presence of tophi. In the De Vera et al. study, information about these disease features was lacking, and the poor case definition of the gouty ...

prevent urate deposition (tophi) in various body tissues and influence the progressive course of chronic tophaceous gout. With accumulating experience in the continuous use of uricosuric agents ...

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...

Among individuals with gout, 94.3% received a physician diagnosis, 99.5% had experienced a flare, and 66.0% reported having a flare in the past 12 months. Tophi were reported among 18.8% of cases.

Other symptoms can include: Decreased range of motion Redness Swelling in finger joints Warm or hot skin around the affected ...

Gout is a prevalent metabolic disorder characterized by urate crystal accumulation in joints, leading to acute arthritis and tophi formation. Despite advancements in management, the incidence and ...

These crystals lead to arthritis and inflammation. A rare, severe, and chronic form of gout that is difficult to treat is called refractory gout. Chronic arthritis, redness tophi (lumps that develop ...