在人类大脑的微观世界中,一道厚度不足头发丝百分之一的生物屏障——糖萼(细胞周基质)(glycocalyx),正悄然主导着一场关乎生死的防御战役。
For years, scientists studying brain aging have focused on proteins and DNA. But what if a crucial piece of the puzzlehas ...
Biological cells often possess thin, hair-like protrusions on their surface known as cilia, which serve various functions ...
Scientists from Germany and Italy have uncovered details of the protective layer that surrounds the fine protrusions of cells ...
These age-related changes to the glycocalyx weaken the blood-brain barrier, Shi found. As the barrier becomes leaky with age, harmful molecules can infiltrate the brain, potentially fueling ...
A recent study published in the journal Nature showed that the dysregulation of the brain endothelial glycocalyx layer impairs the blood-brain barrier (BBB) in disease and aging. The BBB forms a ...
In a study in aging mice, Shi has uncovered striking age-related changes in the sugary coating – called the glycocalyx – on cells that form the blood-brain barrier, a structure that protects ...
The study looked at the effects of disruptions to the glycocalyx, a sugary coating on cells. The glycocalyx is a key component of the blood-brain barrier because it serves as a gateway to the brain.
“We’re stepping outside for the first time and trying to make sense of what’s out there.” In a study in aging mice, Shi has uncovered striking age-related changes in the sugary coating – called the ...
Biological cells often possess thin, hair-like protrusions on their surface known as cilia, which serve various functions ranging from movement to sensing environmental signals. Researchers from ...
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