Among the TCGA findings are the identification of many gene mutations involved in GBM, including three previously unrecognized mutations that occur with significant frequency; and the delineation ...

We performed genomewide analyses of 293 lower-grade gliomas from adults, incorporating exome sequence, DNA copy number, DNA methylation, messenger RNA expression, microRNA expression, and targeted ...

Further validation included analyzing glioma datasets from The Cancer Genome Atlas (TCGA) to confirm the prevalence of ...

In a paper published Sept. 4, 2008, in the advance online edition of the journal "Nature," the TCGA team describes the discovery of new genetic mutations and other types of DNA alterations with ...

A glioma that looks relatively unaggressive under a microscope may still have a lethal potential. That is a key finding of research recently published by the Cancer Genome Atlas Research Network ...

The TCGA researchers expanded on previous studies, which had established gene expression profiling as a means to identify distinct subgroups of GBM. "We discovered a bundle of events that ...

Gliomas are the most common malignant primary brain tumor in adults and are categorized by the World Health Organization (WHO) into distinct tumor subtypes and tumor grades according to a ...

Optic glioma is a brain tumor that grows slowly. Around 75% of diagnoses occur in children younger than 10 years old. Optic glioma accounts for approximately 5% of all childhood brain tumors.