The primary goal of mouse mutagenesis programmes is to develop a fundamental research infrastructure for mammalian functional genomics and to produce human disease models. Many large-scale ...

Researchers at Karolinska Institutet have uncovered new insights into the mechanisms underlying autism spectrum disorder (ASD ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends ...

Collaborative research is driving the development of future treatments to ease symptoms of autism and epilepsy. The ...

In the new study, the researchers observed that all Dp1Tyb mice—a genetically modified mouse model with an extra copy of a genetic region on mouse chromosome 16 (which mirrors human chromosome 21)—had ...

Studying a diverse and peculiar genus of mice offers researchers a window into the genetic and neural underpinnings of behavior.

The genetic cause for the most common type of hearing loss in children with Down syndrome has been identified in mice by researchers at UCL, the ...

More information: Meirui An et al, In vivo base editing extends lifespan of a humanized mouse model of prion disease, Nature Medicine (2025). DOI: 10.1038/s41591-024-03466-w . www.nature.com ...

Two new compounds may be able to treat retinitis pigmentosa, a group of inherited eye diseases that cause blindness. The ...

The dynamic interplay between genetic, molecular and behavioral elements ... reduces post-pubertal social behavior in a mouse model of fragile X syndrome” by Y Sakamoto and colleagues and ...